Frequently Asked Questions (FAQs)
1. What is OGP?
OGP is a comprehensive repository of experimentally characterized O-glycoproteins. There is also a prediction tool for O-glycosylated sites based on currently recorded O-glycosylation data. This database will surely facilitate research in O-glycosylation research.
2. What is the glycan form recorded in OGP?
It is the ultimately goal to unravel the topology and linkages of each monosaccharide with a glycan. However, due to the deficiency and limitation of current analytical methods, most of the recorded glycans are presented in composition forms. However there does exist some glycans with linkage information in this database with confident experiment proofs capable of confirming its topological structures.
3. Was there any other types of O-glycosylation presented in OGP?
There are many other types of O-glycosylation found on proteins, in the current version of OGP, we only focus on GalNAc-initiated O-glycosylation. Other forms of O-glycosylation like O-mannose and O-Fucose initiated O-glycosylation will be included in future version of OGP to make it a more powerful tool for O-glycosylation research.